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Correction: Rapid synthesis of internal peptidyl α-ketoamides by on resin oxidation for the construction of rhomboid protease inhibitors

Tim Van Kersavonda, Raphael Konopatzkia, Merel A. T. van der Plasscheb, Jian Yangb and Steven H. L. Verhelst*ab
aLeibniz Institute for Analytical Sciences ISAS, e.V., Otto-Hahn-Str. 6b, 44227 Dortmund, Germany
bKU Leuven, Department of Cellular and Molecular Medicine, Laboratory of Chemical Biology, Herestr. 49 box 802, 3000 Leuven, Belgium. E-mail: steven.verhelst@kuleuven.be

Received 19th February 2021 , Accepted 19th February 2021

First published on 1st March 2021


Abstract

Correction for ‘Rapid synthesis of internal peptidyl α-ketoamides by on resin oxidation for the construction of rhomboid protease inhibitors’ by Tim Van Kersavond et al., RSC Adv., 2021, 11, 4196–4199, DOI: 10.1039/D0RA10614C.


The authors regret that an incorrect version of Fig. 1 was presented in the original manuscript. The R-group in compound 7 was incorrectly indicated as (CH2)5Ph. The corrected version of the figure with the R group as (CH2)4Ph is shown below.
image file: d1ra90086b-f1.tif
Fig. 1 Examples of rhomboid inhibitors. (A) 4-Chloro-isocoumarins (1), β-lactams (2), benzoxazinones (3) and fluorophosphonates (4). (B) α-Ketoamide rhomboid inhibitors (5–7). The peptidic element in the non-primed site is indicated with the P1–P4 position according to the Schechter and Berger protease substrate nomenclature.1

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.

References

  1. I. Schechter and A. Berger, Biochem. Biophys. Res. Commun., 1967, 27, 157–162 CrossRef CAS.

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