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Correction: Laser cleavable probes for in situ multiplexed glycan detection by single cell mass spectrometry

Jing Hanab, Xi Huanga, Huihui Liua, Jiyun Wanga, Caiqiao Xiong*a and Zongxiu Nie*abc
aBeijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. E-mail: znie@iccas.ac.cn
bUniversity of the Chinese Academy of Sciences, Beijing 100049, China
cNational Center for Mass Spectrometry in Beijing, Beijing 100049, China

Received 19th December 2019 , Accepted 19th December 2019

First published on 9th January 2020


Correction for ‘Laser cleavable probes for in situ multiplexed glycan detection by single cell mass spectrometry’ by Jing Han et al., Chem. Sci., 2019, 10, 10958–10962.


The authors regret that there is some ambiguity over the origin of the probe molecule and would like to clarify that in the manuscript they presented a multiplexed and sensitive glycan detection approach based on laser cleavable probes.

In the article a multiplexed and sensitive glycan detection approach based on laser cleavable probes is developed. In this method, four kinds of glycans at the surface of single cell and tissue were recognized by their specific lectins, and sensitive mass spectrometry detection was achieved by combining the lectins with laser cleavable probes with different mass tags.

Regarding the synthesis of the laser cleavable probes, the four laser cleavable probes 1–4 were previously synthesized by Moon et al.1 (reference 31 in the original article) and details of the syntheses are provided in the ESI (Scheme S1 and Fig. S1–S8). These probes were chosen as the mass tags to detect glycans for the first time.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.

References

  1. N. Kang, J. M. Lee, A. Jeon, H. B. Oh and B. Moon, Tetrahedron, 2016, 72, 5612–5619 CrossRef CAS.

Footnote

Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc90270h

This journal is © The Royal Society of Chemistry 2020