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Correction: Enantioselective, convergent synthesis of the ineleganolide core by a tandem annulation cascade†
Robert A.
Craig
II
,
Jennifer L.
Roizen
,
Russell C.
Smith
,
Amanda C.
Jones
,
Scott C.
Virgil
and
Brian M.
Stoltz
*
Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA. E-mail: stolz@caltech.edu
First published on 14th January 2019
Abstract
Correction for ‘Enantioselective, convergent synthesis of the ineleganolide core by a tandem annulation cascade’ by Robert A. Craig II et al., Chem. Sci., 2017, 8, 507–514.
Since publication of the original manuscript, the authors have carried out some additional research and can now unambiguously confirm the reassignment of a few late-stage, intermediate compounds that were incorrectly assigned in the original manuscript. Specifically, they have obtained an X-ray structure of the product of Amberlyst® treatment of the mixture of compounds 32 and S2 and the product obtained is epimeric at C7. To avoid confusion, this new product is called product ent-12A. An updated and corrected Scheme 5 is provided below.
 | ||
| Scheme 1 Synthesis of ent-isoineleganolide A (29) and X-ray crystal structure of ent-epi-isoineleganolide B (ent-12A). | ||
Additional Supplementary Information is provided, containing details of the newly solved X-ray crystal structure.
For a complete discussion, please see the authors’ recently published account of their research program toward the enantioselective synthesis of ineleganolide.1
The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.
References
- R. A. Craig II, R. C. Smith, J. L. Roizen, A. C. Jones, S. C. Virgil and B. M. Stoltz, J. Org. Chem., 2018, 83, 3467 CrossRef PubMed.
Footnote |
| † Electronic supplementary information (ESI) available: X-ray crystal structure analysis of enone ent-12A. CCDC 1885720. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc90236d |
| This journal is © The Royal Society of Chemistry 2019 |