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DOI: 10.1039/C8CC90504E (Correction) Chem. Commun., 2018, 54, 13161-13161

Correction: CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins

Edward S. Hems , Ben A. Wagstaff , Gerhard Saalbach and Robert A. Field *
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK. E-mail: rob.field@jic.ac.uk

Received 1st November 2018 , Accepted 1st November 2018

First published on 13th November 2018

Abstract

Correction for 'CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins' by Edward S. Hems et al., Chem. Commun., 2018, 54, 12234–12237.

The authors regret that Table 1 was displayed incorrectly in the original article. The correct version is shown below.
Table 1 Prymnesium strains and corresponding HRMS identification of 8 prymnesin compounds, including prymnesin-A1 and -A2 originally reported by Igarashi et al.,8,9 based on MS/HRMS and subsequent labelling with 3-azido-7-hydroxycoumarin (3). Masses reported correspond to [M + 2H]2+ ion, unless denoted with a ‘*’ which reports the [M + Na + H]2+ ion. Toxins that share the same backbone only have 1 value reported for the clicked aglycone, which is an average signal for the aglycone from all toxins
Strain Prymnesin-type Elemental composition of aglycone [M-glycone + 2H]2+ Elemental composition [M + 2H]2+ [M + Na + H]2+* Elemental composition of ‘clicked’ toxin (aglycone) [M-glycone + azidocoumarin + 2H]2+
P. parvum 946/6 Prymnesin-A1 C91H128Cl3NO31 (Δ0.6 ppm) 918.8835 C107H154Cl3NO44 (Δ4.0 ppm) 1131.9482 C100H133Cl3N4O34 (Δ4.0 ppm) 1020.3965
Prymnesin-A2 C91H128Cl3NO31 (Δ1.3 ppm) 918.8853 C96H136Cl3NO35 (Δ1.5 ppm) 984.9037 " "
P. parvum 94A Prymnesin-A1 C91H128Cl3NO31 (Δ4.6 ppm) 918.8798 C107H154Cl3NO44 (Δ6.0 ppm) 1131.9460 C100H133Cl3N4O34 (Δ6.4 ppm) 1020.3941
Prymnesin-A2 C91H128Cl3NO31 (Δ4.2 ppm) 918.8802 C96H136Cl3NO35 (Δ5.5 ppm) 984.8998 " "
P. sp. 595 Prymnesin-B6 C85H121Cl2NO29 (Δ2.1 ppm) 845.8756 C85H121Cl2NO29 (Δ2.1 ppm) 845.8756 C94H126Cl2N4O32 (Δ5.8 ppm) 947.3884
Prymnesin-B7 C85H121Cl2NO29 (Δ3.4 ppm) 845.8745 C91H131Cl2NO34 (Δ4.9 ppm) 926.8992 " "
P. patelliferum 527D Prymnesin-D1 C85H114Cl3NO32 (Δ0.3 ppm) 883.8270 C101H140Cl3NO45 (Δ0.5 ppm) 1107.8870* C94H119Cl3N4O35 (Δ0.4 ppm) 985.3437
Prymnesin-D2 C85H114Cl3NO32 (Δ3.4 ppm) 883.8298 C90H122Cl3NO36 (Δ0.5 ppm) 949.8484 " "
Prymnesin-D3 C85H113Cl2NO32 (Δ0.2 ppm) 865.8386 C101H139Cl2NO45 (Δ0.7 ppm) 1078.9063 C94H118Cl2N4O35 (Δ4.1 ppm) 967.3510
Prymnesin-D4 C85H113Cl2NO32 (Δ0.4 ppm) 865.8388 C90H121Cl2NO36 (Δ0.7 ppm) 931.8589 " "

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.

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