Daniela Delli Castelli, Lorenzo Tei, Fabio Carniato, Silvio Aime and Mauro Botta
Chem. Commun., 2018,54, 2004-2007
DOI:
10.1039/C8CC00193F,
Communication
An unexpectedly slow exchange rate has been observed for the coordinated water molecule of [Yb(AAZTA)(H2O)]− using 1H-NMR and CEST-MRI studies. This made it possible for the first time to exploit the bound water molecule of a LnIII complex with carboxylic donor groups for CEST imaging. This result envisages the development of a new family of thermodynamically stable ParaCEST probes based on anionic chelates.