Matthew D. Stephens, Nisakorn Yodsanit and Christian Melander
Org. Biomol. Chem., 2016,14, 6853-6856
DOI:
10.1039/C6OB00706F,
Paper
A small molecule library consisting of 45 compounds was synthesized based on the bacterial metabolite ethyl N-(2-phenethyl) carbamate. Screening of the compounds revealed a potent analogue capabale of inhibiting several strains of Methicillin Resistant S. aureus biofilms with low to moderate micromolar IC50 values.