Chun Liu, Xinmin Li, Chao Liu, Xinnan Wang and Jieshan Qiu
RSC Adv., 2015,5, 54312-54315
DOI:
10.1039/C5RA10001A,
Communication
A simple and environment-friendly protocol for the palladium-catalyzed ligand-free Suzuki–Miyaura reaction of heteroaryl halides with N-methyliminodiacetic acid (MIDA) boronates is developed. The reaction is performed in water as the sole medium and allows the preparation of a variety of heterobiaryls in excellent yields.