Herein, we have described, a ‘Click Chemistry’ protocol for the rapid synthesis of 1,2,3-triazoles in water. (DHQD)2PHAL has been found to be an excellent accelerating ligand for the copper(I)-catalyzed azide–alkyne cycloaddition reaction under air. The procedure is simple, efficient, environmentally-friendly and the products were isolated in excellent yields with high purity.
A. A. Ali, M. Chetia, P. J. Saikia and D. Sarma, RSC Adv., 2014, 4, 64388 DOI: 10.1039/C4RA12572J
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