Issue 31, 2014
From the journal:

Chemical Communications

A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding†

John B. Mangrum,‡a   Brigitte J. Engelmann,‡a   Erica J. Peterson,a   John J. Ryan,b   Susan J. Berners-Pricec  and  Nicholas P. Farrell*ac  

* Corresponding authors

a Department of Chemistry, Virginia Commonwealth University, Richmond, Virginia 23284, USA
E-mail: npfarrell@vcu.edu

b Department of Biology, Virginia Commonwealth University, Richmond, Virginia 23284, USA

c Institute for Glycomics, Griffith University, Gold Coast, Queensland 4222, Australia

Abstract

Metalloglycomics – the effects of defined coordination compounds on oligosaccharides and their structure and function – opens new areas for bioinorganic chemistry and expands its systematic study to the third major class of biomolecules after DNA/RNA and proteins.

Graphical abstract: A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

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Article information

DOI
https://doi.org/10.1039/C3CC49695C
Article type
Communication
Submitted
22 Dec 2013
Accepted
17 Jan 2014
First published
20 Jan 2014

Chem. Commun., 2014,50, 4056-4058

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A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

J. B. Mangrum, B. J. Engelmann, E. J. Peterson, J. J. Ryan, S. J. Berners-Price and N. P. Farrell, Chem. Commun., 2014, 50, 4056 DOI: 10.1039/C3CC49695C

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