Issue 41, 2013
From the journal:

Organic & Biomolecular Chemistry

Synthesis of highly functionalized macrocycles by tandem multicomponent reactions and intramolecular Sonogashira cross-coupling†

Teng-fei Niu,a   Mu Sun,a   Mei-fang Lv,a   Wen-bin Yia  and  Chun Cai*a  

* Corresponding authors

a Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, P. R. China
E-mail: c.cai@mail.njust.edu.cn
Fax: +86-25-84315030

Abstract

An efficient chemoselective process for the synthesis of 14- and 15-membered triazole-containing macrocycle compounds has been developed through the combination of two multicomponent reactions and an intramolecular Sonogashira cross-coupling reaction.

Graphical abstract: Synthesis of highly functionalized macrocycles by tandem multicomponent reactions and intramolecular Sonogashira cross-coupling

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Article information

DOI
https://doi.org/10.1039/C3OB41367E
Article type
Paper
Submitted
04 Jul 2013
Accepted
02 Sep 2013
First published
03 Sep 2013

Org. Biomol. Chem., 2013,11, 7232-7238

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Synthesis of highly functionalized macrocycles by tandem multicomponent reactions and intramolecular Sonogashira cross-coupling

T. Niu, M. Sun, M. Lv, W. Yi and C. Cai, Org. Biomol. Chem., 2013, 11, 7232 DOI: 10.1039/C3OB41367E

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