Issue 41, 2013
From the journal:

Organic & Biomolecular Chemistry

Synthesis of the C1–C25 southern domain of spirastrellolides B and F†

Gowravaram Sabitha,*a   Allu Senkara Raoa  and  J. S. Yadava  

* Corresponding authors

a Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 607, India
E-mail: gowravaramsr@yahoo.com, sabitha@iict.res.in
Fax: +91-40-27160512

Abstract

Synthesis of the C1–C25 ABC spiroketal ring system of spirastrellolides B and F has been executed. The synthetic strategy relied on radical cyclization, HWE olefination, (BDP)CuH conjugate reduction and spiro acetalization reactions.

Graphical abstract: Synthesis of the C1–C25 southern domain of spirastrellolides B and F

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Article information

DOI
https://doi.org/10.1039/C3OB41345D
Article type
Paper
Submitted
01 Jul 2013
Accepted
30 Aug 2013
First published
30 Aug 2013

Org. Biomol. Chem., 2013,11, 7218-7231

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Synthesis of the C1–C25 southern domain of spirastrellolides B and F

G. Sabitha, A. S. Rao and J. S. Yadav, Org. Biomol. Chem., 2013, 11, 7218 DOI: 10.1039/C3OB41345D

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