Issue 4, 2012

Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

Abstract

A series of ruthenium complexes containing bis-benzimidazole derivatives have been synthesized and identified as able to target mitochondria and induce caspase-dependent apoptosis in cancer cells through superoxide overproduction.

Graphical abstract: Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

Supplementary files

Article information

Article type
Communication
Submitted
16 Oct 2011
Accepted
15 Nov 2011
First published
09 Dec 2011

Dalton Trans., 2012,41, 1138-1141

Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

L. Li, Y. Wong, T. Chen, C. Fan and W. Zheng, Dalton Trans., 2012, 41, 1138 DOI: 10.1039/C1DT11950H

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