The first Au-nanoparticles catalyzed green synthesis of propargylamines via a three-component coupling reaction of aldehyde, alkyne and amine

Abstract

Recyclable Au-nanoparticles provide an efficient, economic, novel route for multi component A³ coupling reaction of aldehyde, amine and alkyne. This method provides the wide range of substrate applicability. This protocol avoids the use of heavy metals, co-catalyst and gives the propargylamine in excellent yields.