The Editorial Board of Molecular BioSystems is made up of an international team of enthusiastic scientists whose expertise covers a broad subject range. Eight members were profiled in Issue 2, 2005 (p. 107); here we introduce Tadhg Begley and Stephen Michnick who recently joined the Board.
Dr. Begley's research is focused on the mechanistic enzymology of complex organic transformations, particularly those found on the vitamin biosynthetic pathways. He is currently working on the biosynthesis of NAD, thiamin, and pyridoxal phosphate In addition to Molecular BioSystems, Dr. Begley is a member of the editorial boards for Vitamins and Hormones, Bioorganic Chemistry, Chemical Biology and Drug Design, and the Wiley Encyclopedia of Chemical Biology. He recently coauthored The organic chemistry of biological pathways with John McMurry.
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| Plate1 Tadhg Begley | ||
Stephen Michnick is Professor of Biochemistry at the University of Montreal. He received his PhD from the University of Toronto with Jeremy P. Carver and postdoctoral training at Harvard University with Profs. Stuart Schreiber and Martin Karplus. He has made several contributions to chemical, structural and genome biology, including studies of the structural basis for actions of FK506, mechanisms of hormone receptor regulation, protein engineering and to pioneering novel approaches to study biochemical networks in living cells. He has received Burroughs-Wellcome New Investigator and MRC Canada Scientist Awards and a Canada Research Chair. He is an Associate of the Canadian Institute for Advanced Research and the scientific founder of Odyssey Thera Inc., a San Francisco based biopharmaceutical firm.
The overall aim of his research is to develop and apply experimental and theoretical approaches to understanding the organization of biochemical networks. To address this challenge a general experimental strategy has been developed allowing for quantitatively probing of the dynamics of molecular interactions in intact, living cells based on Protein fragment Complementation Assays (PCA). His team are seeking to go from descriptive to quantitative representations of biochemical networks at an individual to whole genome level.
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| Plate2 Stephen Michnick | ||
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