Issue 9, 2001

A novel radical cyclization of 2-bromoindoles. Synthesis of hexahydropyrrolo[3,4-b]indoles

Abstract

Hexahydropyrrolo[3,4-b]indoles 6, 10, and 13 are obtained from 2-bromo-3-carboxamides 5, 9, and 12, respectively, by a 1,5-radical translocation process followed by 5-endo-trig cyclization to the indole C-2 position.

Article information

Article type
Communication
Submitted
16 Feb 2001
Accepted
14 Mar 2001
First published
17 Apr 2001

Chem. Commun., 2001, 805-806

A novel radical cyclization of 2-bromoindoles. Synthesis of hexahydropyrrolo[3,4-b]indoles

G. W. Gribble, H. L. Fraser and J. C. Badenock, Chem. Commun., 2001, 805 DOI: 10.1039/B101859K

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