1,3-Dipolar Cycloaddition of Arylnitrile Oxides to Some Exocyclic Alkenes and Regioselective Synthesis of Spiro Isoxazolines

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Nawal Mishriky, Fahmy M. Asaad, Yehia A. Ibrahim and Adel S. Girgis


Abstract

The cycloaddition of arylnitrile N-oxides to the exocyclic double bond of arylmethylidenes derived from indane-1,3-dione 1a–c, indan-1-one 1d–f and 1-tetralone 1g–i afforded the spiroisoxazolines 2a–l with high regioselectivity and not the corresponding isomers 3a–l.


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