The First Preparation of 6β-Bromo Codeine and Morphine Derivatives. Kinetic vs. Thermodynamic Control
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Csaba Simon, Sándor Hosztafi and Sándor Makleit
Abstract
Starting from the hydrogen halide salts of morphine and codeine derivatives, 6α-halogeno(Cl, Br)-substituted codeine and morphine derivatives have been prepared under Mitsunobu conditions.
References
Cs. Simon, S. Hosztafi and S. Makleit, Tetrahedron Lett., 1993, 34, 6475 Search PubMed.