Effect of a-strain on a synthesis of cis-fused 4a-aryloctahydro-1H-cyclopenta[c]pyridine derivatives through tandem radical cyclisation of an α-acylamino–polyene system
Abstract
An efficient synthesis of the cis-fused 4a-aryloctahydro-1H-cyclopenta[c]pyridine ring sustem, an analogue of 4a-aryidecahydroisoquinoline, was achieved through a teandem redical approach by cyclisation of free radical–polyene species.