The preparation of 6-amino-5-methyl isoquinolin-1 (2H)-one is described. Starting from this key intermediate, several derivatives of 5H-pyrido[3′,4′ :4,5]pyrrolo[2,3-g]isoquinoline substituted with various alkyl amino-groups at their 10-position have been synthesized.
C. Ducrocq, E. Bisagni, C. Rivalle and J. Lhoste, J. Chem. Soc., Perkin Trans. 1, 1979, 142 DOI: 10.1039/P19790000142
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