6,11-Dimethyl-5H-pyrido[3′,4′:4,5]pyrrolo[2,3-g]isoquinoline: a new aza-analogue of ellipticine

Abstract

6,11-Dimethyl-5H-pyrido[3′,4′:4,5]pyrrolo[2,3-g]isoquinoline, an aza-analogue of ellipticine, has been prepared in four steps, starting from 4-chloro-3-nitropyridine and 6-amino-5,8-dimethylisoquinoline. Different unsuccessful attempts to prepare various pyrido[3′,4′:4,5]pyrrolo[2,3-g]isoquinolines by application of methods successfully used in the synthesis of several pyrido[4,3-b]carbazoles, are described.