Novel synthesis of isothiocyanatophosphoranes and isothiocyanatophosphonium salts via ligand substitution. Versatile reagents for converting hydroxy groups into thiocyanate and isothiocyanate functions

Abstract

Alkoxy- or acyloxy-isothiocyanatophosphoranes (7) and phosphonium salts (12), prepared under mild conditions by stepwise ligand substitution from (5) and (11), respectively, decompose in excellent yield into the corresponding thiocyanato (9) and isothiocyanato (10) derivatives, thus providing a new method of synthesis of (9) and (10).