Rearrangements of bicyclo[3,2,0]heptan-6-ones. Synthesis of potential prostanoid precursors
Abstract
3-endo-Alkoxy-2-exo-bromobicyclo[3,2,0]heptan-6-ones rearrange under basic conditions and in the presence of cyanide ion to give 5-endo-alkoxy-7-anti-cyanobicyclo[2,2,1]heptan-2-ones.