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Issue 18, 2015
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Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

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Abstract

The synthesis of a zinc porphyrin derivative possessing eight triethoxysilyl groups was performed through a CuAAC-click reaction. This porphyrin was covalently entrapped in ethenylene-bridged mesoporous organosilica nanoparticles which efficiently allowed performing doxorubicin delivery and two-photon imaging of breast cancer cells.

Graphical abstract: Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

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Publication details

The article was received on 13 Feb 2015, accepted on 10 Apr 2015 and first published on 10 Apr 2015


Article type: Communication
DOI: 10.1039/C5TB00315F
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Citation: J. Mater. Chem. B, 2015,3, 3681-3684

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    Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

    C. Mauriello-Jimenez, J. Croissant, M. Maynadier, X. Cattoën, M. Wong Chi Man, J. Vergnaud, V. Chaleix, V. Sol, M. Garcia, M. Gary-Bobo, L. Raehm and J. Durand, J. Mater. Chem. B, 2015, 3, 3681
    DOI: 10.1039/C5TB00315F

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