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Issue 62, 2014
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A simple label-free rhodamine 6G SERS probe for quantitative analysis of trace As3+ in an aptamer–nanosol

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Abstract

Gold nanoparticles (NGs) were modified by the aptamer (ssDNA) to prepare a NGssDNA probe for As3+. In pH 8.0 HEPES buffer solution containing 50 mmol L−1 NaCl, rhodamine 6G (Rh6G) molecules adsorbed on the NGssDNA sol substrate exhibited a strong surface-enhanced Raman scattering peak (SERS) at 1358 cm−1. Upon addition of As3+, it reacts with the NGssDNA probe to form a stable As–ssDNA complex and release NGs that were aggregated to the NG aggregates (NGAs) as a substrate, in which Rh6G SERS activity is very weak. With the increase of As3+ concentration, the SERS peak decreased at 1358 cm−1 due to more NGAs forming. The decreased SERS intensity responds linearly with the concentration of As3+ over 0.288–23.04 ng mL−1, with a detection limit of 0.1 ng mL−1.

Graphical abstract: A simple label-free rhodamine 6G SERS probe for quantitative analysis of trace As3+ in an aptamer–nanosol

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Publication details

The article was received on 12 May 2014, accepted on 22 Jul 2014 and first published on 23 Jul 2014


Article type: Communication
DOI: 10.1039/C4RA04416A
Citation: RSC Adv., 2014,4, 32960-32964
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    A simple label-free rhodamine 6G SERS probe for quantitative analysis of trace As3+ in an aptamer–nanosol

    L. Ye, G. Wen, J. Dong, Y. Luo, Q. Liu, A. Liang and Z. Jiang, RSC Adv., 2014, 4, 32960
    DOI: 10.1039/C4RA04416A

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