Jump to main content
Jump to site search

Issue 11, 2021
Previous Article Next Article

Iron-catalyzed para-selective C–H silylation of benzamide derivatives with chlorosilanes

Author affiliations

Abstract

Site-selective C–H silylation has emerged as an efficient tool that can be used to simplify the synthesis of organosilicon compounds; however, catalytic para-selective C–H silylation of electron-deficient arenes has remained a much less explored area. Herein, we report an iron-enabled para-selective C–H silylation of benzamide derivatives with chlorosilanes, which constitutes an efficient and general route for the synthesis of a wide range of para-silicon functionalized benzamides from easily accessible starting materials.

Graphical abstract: Iron-catalyzed para-selective C–H silylation of benzamide derivatives with chlorosilanes

Back to tab navigation

Associated articles

Supplementary files

Article information


Submitted
11 Feb 2021
Accepted
17 Mar 2021
First published
23 Mar 2021

Org. Chem. Front., 2021,8, 2442-2448
Article type
Research Article

Iron-catalyzed para-selective C–H silylation of benzamide derivatives with chlorosilanes

P. Liu, N. Hao, D. Yang, L. Wan, T. Wang, T. Zhang, R. Zhou, X. Cong and J. Kong, Org. Chem. Front., 2021, 8, 2442 DOI: 10.1039/D1QO00243K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements