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Issue 2, 2012
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Facile glycosylation of dendrimers for eliciting specific cell–material interactions

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Abstract

Taking advantage of the reactivity between reducing glycans and hydrazides, a facile and general approach is demonstrated to conjugate glycan epitopes to polyamidoamine (PAMAM) based dendrimers. Using HepG2 cells, it is shown that parallel studies of different glycodendrimers allowed comparison and identification of multivalent conjugates with specific cell-binding capabilities.

Graphical abstract: Facile glycosylation of dendrimers for eliciting specific cell–material interactions

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Supplementary files

Article information


Submitted
08 Sep 2011
Accepted
11 Nov 2011
First published
29 Nov 2011

Polym. Chem., 2012,3, 310-313
Article type
Communication

Facile glycosylation of dendrimers for eliciting specific cell–material interactions

X. Liu, J. Liu and Y. Luo, Polym. Chem., 2012, 3, 310
DOI: 10.1039/C1PY00404B

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