SCHEDULED MAINTENANCE
In the presence of lithium diisopropylamide at low temperature, the anion of the amino nitrile 1 is alkylated with epibromohydrin to give an acetonyl derivative 3; allene oxide is invoked as the reactive intermediate.
F. Vergne, D. J. Aitken and H. Husson, J. Chem. Soc., Perkin Trans. 1, 1991, 1346 DOI: 10.1039/P19910001346
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