Issue 1, 2006
From the journal:

Organic & Biomolecular Chemistry

Mitsunobu dehydration of N-Boc neomycin B†

Sabina Quader,a   Sue E. Boyd,a   Ian D. Jenkins*ab  and  Todd A. Houston*a  

* Corresponding authors

a Eskitis Institute, Griffith University, Nathan, Brisbane, QLD, Australia
E-mail: T.Houston@griffith.edu.au
Tel: +617 3735 4115

b Natural Product Discovery, Griffith University, Nathan, Brisbane, QLD, Australia
E-mail: I.Jenkins@griffith.edu.au
Tel: +617 3735 6025

Abstract

Reaction of hexa-N-Boc neomycin B with TPP and DIAD in toluene results in the formation of an epoxide in ring IV, not an aziridine or azetidine as previously reported.

Graphical abstract: Mitsunobu dehydration of N-Boc neomycin B

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Article information

DOI
https://doi.org/10.1039/B513113H
Article type
Communication
Submitted
16 Sep 2005
Accepted
08 Nov 2005
First published
22 Nov 2005

Org. Biomol. Chem., 2006,4, 36-37

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Mitsunobu dehydration of N-Boc neomycin B

S. Quader, S. E. Boyd, I. D. Jenkins and T. A. Houston, Org. Biomol. Chem., 2006, 4, 36 DOI: 10.1039/B513113H

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