Jump to main content
Jump to site search

Issue 25, 2015
Previous Article Next Article

Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level

Author affiliations

Abstract

DNA origami has been used to orchestrate reactions with nano-precision using a variety of biomolecules. Here, the dynamics of albumin-assisted, localized single-molecule DNA polymerization by terminal deoxynucleotidyl transferase on a 2D DNA origami are monitored using AFM in liquid. Direct visualization of the surface activity revealed the mechanics of growth.

Graphical abstract: Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level

Back to tab navigation

Supplementary files

Article information


Submitted
26 Mar 2015
Accepted
29 May 2015
First published
03 Jun 2015

Nanoscale, 2015,7, 10970-10973
Article type
Communication
Author version available

Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level

A. H. Okholm, H. Aslan, F. Besenbacher, M. Dong and J. Kjems, Nanoscale, 2015, 7, 10970
DOI: 10.1039/C5NR01945A

Social activity

Search articles by author

Spotlight

Advertisements