Purines, pyrimidines, and imidazoles. Part XXXV. Potentiometric and spectroscopic studies of some imidazoles related to intermediates in the biosynthesis de novo of purine nucleotides

Abstract

Ionisation constants of 5-amino-1-β-D-ribofuranosylimidazole-4-carboxylic acid 5′-phosphate (C-AIR) an intermediate in purine nucleotide biosynthesis, and of several related 5-aminoimidazoles, have been measured by use of both spectrophotometric and potentiometric techniques. Assignments have been made and compared with those for related compounds.