Jump to main content
Jump to site search

Issue 3, 2014
Previous Article Next Article

Enzymatic halogenation of the phenolic monoterpenes thymol and carvacrol with chloroperoxidase

Author affiliations

Abstract

The conversion of the phenolic monoterpenes thymol and carvacrol into antimicrobials by (electro)-chemoenzymatic halogenation was investigated using a chloroperoxidase (CPO) catalyzed process. The CPO catalysed process enables for the first time the biotechnological production of chlorothymol, chlorocarvacrol and bromothymol as well as a dichlorothymol with high conversion rates, total turnover numbers and space time yields of up to 90%, 164 000 and 4.6 mM h−1, respectively.

Graphical abstract: Enzymatic halogenation of the phenolic monoterpenes thymol and carvacrol with chloroperoxidase

Back to tab navigation

Supplementary files

Article information


Submitted
04 Nov 2013
Accepted
28 Nov 2013
First published
28 Nov 2013

Green Chem., 2014,16, 1104-1108
Article type
Communication
Author version available

Enzymatic halogenation of the phenolic monoterpenes thymol and carvacrol with chloroperoxidase

L. Getrey, T. Krieg, F. Hollmann, J. Schrader and D. Holtmann, Green Chem., 2014, 16, 1104
DOI: 10.1039/C3GC42269K

Social activity

Search articles by author

Spotlight

Advertisements