SCHEDULED MAINTENANCE
The catalytic role of hydrophobic co-solutes in DNA strand exchange is demonstrated by FRET kinetics. Two mechanisms that contribute to this are base stacking destabilisation and nucleation-promoted DNA strand invasion. We propose that hydrophobic catalysis is involved in the strand-exchange activity of recombination enzymes.
B. Feng, F. Westerlund and B. Nordén, Chem. Commun., 2015, 51, 7390 DOI: 10.1039/C5CC01515D
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