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Issue 42, 2014
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Amino group binding peptide aptamers with double disulphide-bridged loops selected by in vitro selection using cDNA display

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Abstract

Peptide aptamers that specifically bind to the amino group on a solid-phase were screened by in vitro selection using the cDNA display method. The identified peptides have a unique structure containing two cyclic loops with disulphide bonds and a linkage region, which were indispensable for molecular recognition.

Graphical abstract: Amino group binding peptide aptamers with double disulphide-bridged loops selected by in vitro selection using cDNA display

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Supplementary files

Article information


Submitted
29 Jan 2014
Accepted
31 Mar 2014
First published
31 Mar 2014

Chem. Commun., 2014,50, 5608-5610
Article type
Communication
Author version available

Amino group binding peptide aptamers with double disulphide-bridged loops selected by in vitro selection using cDNA display

Y. Mochizuki, K. Nishigaki and N. Nemoto, Chem. Commun., 2014, 50, 5608
DOI: 10.1039/C4CC00799A

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