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Issue 84, 2013
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A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end

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Abstract

Here we report a new strategy for designing a graphene oxide (GO)-quenched dye-labeled DNA hairpin probe by utilizing the sticky end adsorbed onto the GO surface. Only introduction of target DNA can alter the orientation of the sticky end, causing the dye to move apart from the GO surface, resulting in fluorescence restoration.

Graphical abstract: A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end

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Publication details

The article was received on 14 Jul 2013, accepted on 25 Aug 2013 and first published on 28 Aug 2013


Article type: Communication
DOI: 10.1039/C3CC45307C
Chem. Commun., 2013,49, 9827-9829

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    A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end

    J. Huang, X. Yang, X. He, K. Wang, Y. He and K. Quan, Chem. Commun., 2013, 49, 9827
    DOI: 10.1039/C3CC45307C

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