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Issue 84, 2013
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A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end

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Abstract

Here we report a new strategy for designing a graphene oxide (GO)-quenched dye-labeled DNA hairpin probe by utilizing the sticky end adsorbed onto the GO surface. Only introduction of target DNA can alter the orientation of the sticky end, causing the dye to move apart from the GO surface, resulting in fluorescence restoration.

Graphical abstract: A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end

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Article information


Submitted
14 Jul 2013
Accepted
25 Aug 2013
First published
28 Aug 2013

Chem. Commun., 2013,49, 9827-9829
Article type
Communication

A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end

J. Huang, X. Yang, X. He, K. Wang, Y. He and K. Quan, Chem. Commun., 2013, 49, 9827
DOI: 10.1039/C3CC45307C

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