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Issue 62, 2012
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Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells

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Abstract

We describe the synthesis, properties, and application of two reversible fluorescent probes, mCy-TemOH and Cy-TemOH, for HOBr sensing and imaging in live cells. The two probes contain a hydroxylamine functional group for the monitoring of HOBr oxidation/ascorbic acid reduction events. Confocal fluorescence microscopy has established the HOBr detection in live-cells.

Graphical abstract: Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells

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The article was received on 07 May 2012, accepted on 12 Jun 2012 and first published on 13 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33264G
Chem. Commun., 2012,48, 7735-7737

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    Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells

    F. Yu, P. Song, P. Li, B. Wang and K. Han, Chem. Commun., 2012, 48, 7735
    DOI: 10.1039/C2CC33264G

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