Issue 14, 2012

When two metal centres are needed instead of one: exclusive induction of Z-DNA by dinuclear metal complexes

Abstract

The B- to Z-DNA transition was very efficiently induced by dinuclear nickel and copper complexes based on the 1,3-bis(1,5,9-triazacyclododecyl) propane ligand but not by the corresponding mononuclear complexes. This dramatically different behaviour is explained by the formation of a macrochelate of the dinuclear complexes to the DNA.

Graphical abstract: When two metal centres are needed instead of one: exclusive induction of Z-DNA by dinuclear metal complexes

Supplementary files

Article information

Article type
Communication
Submitted
18 Oct 2011
Accepted
24 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 1961-1963

When two metal centres are needed instead of one: exclusive induction of Z-DNA by dinuclear metal complexes

A. Medina-Molner and B. Spingler, Chem. Commun., 2012, 48, 1961 DOI: 10.1039/C2CC16483C

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