Issue 39, 2011
From the journal:

Chemical Communications

Ruthenium(ii) polypyridyl complexes as carriers for DNA delivery†

Satish S. Bhat,a   Avinash S. Kumbhar,*a   Anupa A. Kumbhar,a   Ayesha Khan,b   Peter Lönneckec  and  Evamarie Hey-Hawkinsc  

* Corresponding authors

a Department of Chemistry, University of Pune, Pune- 411007, India
E-mail: askum@chem.unipune.ac.in
Fax: +91-020-25691728

b Institute of Bioinformatics and Biotechnology, University of Pune, India

c Faculty of Chemistry and Mineralogy, Department of Inorganic Chemistry, Universität Leipzig, Johannisallee 29, Leipzig, Germany

Abstract

Two novel water soluble ruthenium(II) complexes [Ru(bpy)2(bqbg)]2+ and [Ru(phen)2(bqbg)]2+ have been structurally characterized and their DNA condensation activity, cytotoxicity, and cellular uptake studies of DNA condensates as potential non-viral DNA carriers were evaluated.

Graphical abstract: Ruthenium(ii) polypyridyl complexes as carriers for DNA delivery

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Article information

DOI
https://doi.org/10.1039/C1CC13863D
Article type
Communication
Submitted
28 Jun 2011
Accepted
23 Aug 2011
First published
06 Sep 2011

Chem. Commun., 2011,47, 11068-11070

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Ruthenium(II) polypyridyl complexes as carriers for DNA delivery

S. S. Bhat, A. S. Kumbhar, A. A. Kumbhar, A. Khan, P. Lönnecke and E. Hey-Hawkins, Chem. Commun., 2011, 47, 11068 DOI: 10.1039/C1CC13863D

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