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Issue 35, 2010
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Probing protease activity by single-fluorescent-protein nanocapsules

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Abstract

We describe a FRET-based protease detection strategy, using a single-fluorescent-protein nanogel as donor and a dark quencher as acceptor linked by a photolabile caged-peptide. This design enables probing of protease activity in a UV-responsive fashion.

Graphical abstract: Probing protease activity by single-fluorescent-protein nanocapsules

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Publication details

The article was received on 17 May 2010, accepted on 30 Jun 2010 and first published on 26 Jul 2010


Article type: Communication
DOI: 10.1039/C0CC01439G
Citation: Chem. Commun., 2010,46, 6467-6469

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    Probing protease activity by single-fluorescent-protein nanocapsules

    Z. Gu, A. Biswas, K. Joo, B. Hu, P. Wang and Y. Tang, Chem. Commun., 2010, 46, 6467
    DOI: 10.1039/C0CC01439G

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