Issue 17, 2010
From the journal:

Chemical Communications

Aerosol fabrication of hollow mesoporous silicananoparticles and encapsulation of l-methionine as a candidate drug cargo†

Xingmao Jiang,ab   Timothy L. Ward,a   Yung-Sung Cheng,b   Juewen Liuc  and  C. Jeffrey Brinker*ade  

* Corresponding authors

a Department of Chemical and Nuclear Engineering and Center for Micro-Engineered Materials, The University of New Mexico, Albuquerque, USA

b Aerosol and Respiratory Dosimetry Program, Lovelace Respiratory Research Institute, Albuquerque, USA

c Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada

d Department of Molecular Genetics and Microbiology, University of New Mexico, USA

e Sandia National Laboratories, MS 1349, Albuquerque, USA
E-mail: cjbrink@sandia.gov
Fax: +1-505-272-7336
Tel: +1-505-272-7627

Abstract

Hollow spherical nanoparticles with ordered mesoporous silica shells were fabricated by evaporation-induced self-assembly using (NH4)2SO4 and cetyltrimethyl ammonium bromide (CTAB) as templates. The model drug, L-methionine, was encapsulated within the spherical void at high loadings by repeated crystallization.

Graphical abstract: Aerosol fabrication of hollow mesoporous silica nanoparticles and encapsulation of l-methionine as a candidate drug cargo

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Article information

DOI
https://doi.org/10.1039/B927025F
Article type
Communication
Submitted
22 Dec 2009
Accepted
03 Mar 2010
First published
25 Mar 2010

Chem. Commun., 2010,46, 3019-3021

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Aerosol fabrication of hollow mesoporous silica nanoparticles and encapsulation of L-methionine as a candidate drug cargo

X. Jiang, T. L. Ward, Y. Cheng, J. Liu and C. J. Brinker, Chem. Commun., 2010, 46, 3019 DOI: 10.1039/B927025F

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