Fe-catalyzed highly selective ring expansion of alkynylcyclopropyl alkanols to cyclobutanols†
Abstract
A Fe-catalytic highly selective ring expansion reaction of alkynylcyclopropyl alkanols to alkynylcyclobutanols via a 1,2-carbon shift under mild conditions was developed. A new class of homogeneous FeCl2/O2 catalytic system was employed in these novel transformations.