A general and useful copper(II)-promoted iodofunctionalization of unsaturated systems
Abstract
A mixture of iodine and CuO·HBF4 reacts stereospecifically with olefins in the presence of a wide variety of nucleophiles (NaNO2, NaSO2Ar, Nal, Et3SiH, MeOPh and H2O) to give the corresponding 2-functionalized iodo compounds; the same reagents also cause iodofunctionalization of 1,3-dienes and acetylenes.