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Issue 15, 2014
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Sensitive fluorescence “off–on” switch system for catechins detection based on water-soluble polythiophene derivatives

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Abstract

Because catechins (CCs) play an important role in human health, we proposed a new CCs detection method relying on a novel fluorescence “off–on” switch system. Water-soluble cationic polythiophene derivatives, denoted as poly 3-{[1-(2-hydrazino-2-oxopropyl)piperidin-4-ylidene]methyl}thiophene hydrochloride (PMTH·HCl), was prepared as a novel fluorescent material. Initially, the fluorescence of PMTH·HCl can be quenched by Cu2+ because of the spontaneous formation of Cu2+–PMTH·HCl assembling dyads, resulting in fluorescence turn off. Then, on the addition of CCs in Cu2+–PMTH·HCl, Cu2+ was separated from PMTH·HCl, producing free PMTH·HCl and stable complex Cu2+–CCs, resulting in the turn on of the fluorescence signal of PMTH·HCl. Meanwhile, the mechanisms of fluorescence quenching and recovery were discussed to provide new ideas for designing sensors based on water-soluble conjugated polymers. This fluorescence “off–on” signal was sensitive to the concentration of CCs. Under optimized conditions, the fluorescence intensity was linear to the concentration of CCs varying from 1.0 × 10−8 to 9.0 × 10−6 mol L−1 (γ = 0.9968), with a detection limit of 3.34 × 10−9 mol L−1. Therefore, an efficient, sensitive, highly selective and practically applicable detection system for CCs has been designed.

Graphical abstract: Sensitive fluorescence “off–on” switch system for catechins detection based on water-soluble polythiophene derivatives

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Article information


Submitted
19 Apr 2014
Accepted
16 May 2014
First published
19 May 2014

Anal. Methods, 2014,6, 5812-5817
Article type
Paper
Author version available

Sensitive fluorescence “off–on” switch system for catechins detection based on water-soluble polythiophene derivatives

Y. Liu, X. Meng, M. Pei, G. Zhang and H. Li, Anal. Methods, 2014, 6, 5812
DOI: 10.1039/C4AY00937A

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