Issue 8, 1995

Estimation and determination of steroid solubility in supercritical carbon dioxide

Abstract

The solubility of ten steroids in supercritical carbon dioxide is reported over a range of temperatures (35–100 °C) and pressures (84–231 kg cm–2). The solubility of testosterone, determined in this work, compares favourably with solubility data previously reported. The use of the solubility parameter and a hydrophobicity term (log P), has been shown to provide a qualitative estimate of steroid solubility.

Article information

Article type
Paper

Analyst, 1995,120, 2153-2157

Estimation and determination of steroid solubility in supercritical carbon dioxide

J. R. Dean, M. Kane, S. Khundker, C. Dowle, R. L. Tranter and P. Jones, Analyst, 1995, 120, 2153 DOI: 10.1039/AN9952002153

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