Alkyldisulfanium salt-mediated difunctionalization of alkenes with NH-sulfoximines

Abstract

The incorporation of a sulfoximine group into parent molecules is of interest. In this work, we report a practical and efficient alkyldisulfanium salt-mediated α-sulfoximidation of alkenes with NH-sulfoximines. This method enables the synthesis of various thioether group-containing alkyl sulfoximines in moderate to good yields. Mild and catalyst-free conditions, readily available substrates and operational simplicity make this method quite attractive in organic synthesis.