PIDA/I2-mediated photo-induced aerobic N-acylation of sulfoximines with methylarenes

Abstract

A visible-light-promoted, PIDA/I₂-mediated acylation of NH-sulfoximines with methylarenes as an acyl source has been achieved. This transition metal and photosensitizer-free approach provides easy access to N-acylsulfoximines via oxidative coupling of sulfoximines with easily available methylarenes without using any peroxide source. Mechanistic investigations suggest the intermediacy of radicals and the importance of molecular oxygen.