Heterogeneous catalysts NiCoSe2 and NiCo2S4 for the effective synthesis of dihydropyrimidine-2-ones/thiones

Abstract

The present study is focused on the synthesis of DHPMs by using NiCoSe₂ and NiCo₂S₄ as heterogeneous catalysts, and they are characterized by using XRD, SEM, TEM, BET and XPS. The NiCoSe₂ and NiCo₂S₄ catalysts proved to be the most suitable catalytic system when compared to conventionally reported catalysts in terms of yield and reaction time. NiCoSe₂ and NiCo₂S₄ are environment-friendly catalysts and can be recycled over 5 cycles with a negligible loss in the catalytic performance. Thus, the synthesized catalysts were successfully utilized in the synthesis of biologically active DHPMs, and all compounds were characterized using mass and NMR spectroscopic techniques.