K2S2O8-promoted rearrangement of nitrones for the synthesis of benzo[d]oxazoles

Abstract

An efficient route for the synthesis of valuable benzoxazoles has been developed through self-oxidative cyclization with N–O bond cleavage. Readily available nitrones were used as the starting material under simple metal-free reaction conditions. Various functional groups are compatible with this green protocol which can be carried out in one pot easily.