Microwave-accelerated and benzoyl peroxide (BPO)-initiated cyclization of 1,5-enynes having cyano groups with cyclic alkanes under metal-free conditions

Abstract

A novel and efficient method for preparing exocyclic indan derivatives, with this method involving benzoyl peroxide (BPO)-initiated cyclization of 1,5-enynes having cyano groups with simple cyclic alkanes under microwave irradiation, has been developed. The presented approach showed advantages of simple conditions, an environmentally friendly protocol, good functional-group tolerance, and high yields of products.