Issue 2, 2022

Purification of quantum dot-based bioprobes with a salting out strategy

Abstract

A salting out strategy is reported for purification of IgG-conjugated QD (IgG-QD) bioprobes. Adding NaCl can precipitate free IgG selectively, while the IgG-QD maintains good colloidal stability. The dynamic light scattering technique reveals that this is due to the relatively positive zeta potential of free IgG than that of the IgG-QD.

Graphical abstract: Purification of quantum dot-based bioprobes with a salting out strategy

Supplementary files

Article information

Article type
Communication
Submitted
23 Jul 2021
Accepted
08 Dec 2021
First published
04 Jan 2022
This article is Open Access
Creative Commons BY license

Nanoscale Adv., 2022,4, 393-396

Purification of quantum dot-based bioprobes with a salting out strategy

Z. Chen and J. Xu, Nanoscale Adv., 2022, 4, 393 DOI: 10.1039/D1NA00569C

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