Issue 10, 2022

Application of scanning electrochemical microscopy for topography imaging of supported lipid bilayers

Abstract

Oxidative stress in cellular environments may cause lipid oxidation and membrane degradation. Therefore, studying the degree of lipid membrane morphological changes by reactive oxygen and nitrogen species will be informative in oxidative stress-based therapies. This study introduces the possibility of using scanning electrochemical microscopy as a powerful imaging technique to follow the topographical changes of a solid-supported lipid bilayer model induced by reactive species produced from gas plasma. The introduced strategy is not limited to investigating the effect of reactive species on the lipid bilayer but could be extended to understand the morphological changes of the lipid bilayer due to the action of membrane proteins or antimicrobial peptides.

Graphical abstract: Application of scanning electrochemical microscopy for topography imaging of supported lipid bilayers

Supplementary files

Article information

Article type
Paper
Submitted
27 Jan 2022
Accepted
01 Feb 2022
First published
24 Feb 2022
This article is Open Access
Creative Commons BY-NC license

Anal. Methods, 2022,14, 1077-1082

Application of scanning electrochemical microscopy for topography imaging of supported lipid bilayers

Z. Nasri, S. Memari, J. Striesow, K. Weltmann, T. von Woedtke and K. Wende, Anal. Methods, 2022, 14, 1077 DOI: 10.1039/D2AY00154C

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements